iPrep is an interactive image preprocessor.
EditByBSEditor: iPrep is an interactive image Preprocessor. It deals with the correction of common long Exposure imaging defects, operating on a collection of source images and allowing the selection of a variety of pre-processing algorithms. The results are visible in a preview window, allowing the processing parameters to be fine-tuned prior to saving the final results.

Features:
Import/export image files in AVI/BMP/FIT format.
Work in colour or monochrome
Subtract dark frames
Apply flat frames
Generate synthetic flats from image files
Eradicate hot and cold Pixels
Contrast stretch
Remove interlacing artefacts

The downloadable ZIP file contains the program iPrep.exe, and a rich text file iPrep.rtf containing a description of its features and how to use them (you can read this file using WordPad.) you can free download iPrep 0.9 now.